1yr
COPD Connect
1yr
Interventions for the management of concomitant COPD and hypertension: A systematic review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40557034/
Background: Chronic obstructive pulmonary disease (COPD) and hypertension are prevalent public health burdens, with hypertension often co-existing in up to 65% of COPD patients and complicating patient management. While numerous...
This systematic review identifies limited, inconsistent evidence on managing COPD with coexisting hypertension, revealing a pressing need for integrated, evidence-based strategies to optimize outcomes and reduce healthcare burdens.
1yr
Linking Lipid Metabolism and Immune Function: New Insights into Chronic Respiratory Diseases - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40559469/
Lipids play important roles in maintaining pulmonary structure, performing physiological functions and controlling the immune status of the lung. There is increasing evidence that lipid metabolism and immune activity are...
Lipid metabolism intricately regulates lung immunity. Its dysfunction drives inflammation and progression in COPD. Targeting lipid mediators offers new avenues for biomarkers and therapies in chronic respiratory diseases.
1yr
A Systematic Review and Meta-Analysis on the Safety and Efficacy of Rosuvastatin as an Adjunctive Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40529224/
Despite the limited number of studies and potential bias, evidence suggests that rosuvastatin improves lung function and reduces inflammation in AECOPD, underscoring its potential value and emphasizing the need for...
Rosuvastatin significantly improves lung function and reduces inflammation in AECOPD patients, suggesting its promise as adjunct therapy. However, more robust trials are needed to confirm these benefits.
1yr
Chronic Obstructive Pulmonary Disease in People with HIV: an Evidence-Based Review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/40529790/
HIV co-infection is a risk factor for the development of COPD. HIV enhances the deleterious effects of exposures such as tobacco smoking, as well as interacting with other drivers of...
HIV accelerates and alters COPD progression through inflammation, immune dysregulation, and environmental interactions. This review highlights unique mechanisms, early onset, and the need for HIV-specific COPD management strategies.