Personalized COPD Care: The Future of Precision-Based Therapies - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39518477/
Chronic obstructive pulmonary disease (COPD) is a progressive respiratory illness characterized by long-standing respiratory symptoms and airflow limitation. It is a major contributor to respiratory disease-related deaths and currently ranked...
COPD, a progressive respiratory disease, is managed with bronchodilators, corticosteroids, and newer targeted therapies. Advancements in identifying phenotypes/endotypes offer personalized treatments, improving outcomes and quality of life.
Psychiatric Disorders in Patients with Chronic Obstructive Pulmonary Disease: Clinical Significance and Treatment Strategies - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39518558/
Chronic obstructive pulmonary disease (COPD) is a debilitating lung disease characterized by chronic airflow limitation and persistent respiratory symptoms. It is a major cause of morbidity and mortality worldwide, significantly...
COPD, a chronic lung disease, often coexists with psychiatric disorders like depression and anxiety, impacting quality of life. Multidisciplinary management addressing both physical and mental health is essential for optimal care.
High flow nasal cannula oxygen therapy versus non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease with acute-moderate hypercapnic respiratory failure: a randomized controlled non-inferiority trial - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39026242/
chictr.org (ChiCTR1800014553). Registered 21 January 2018, http://www.chictr.org.cn.
A randomized trial found high-flow nasal cannula oxygen (HFNC) less effective than non-invasive ventilation (NIV) for initial treatment of acute hypercapnic respiratory failure in AECOPD patients.
The Emerging Role of Alarmin-Targeting Biologics in the Treatment of Patients With COPD - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/39631681/
Biologics targeting inflammatory pathways may be effective treatments for specific patients with COPD.
Chronic obstructive pulmonary disease (COPD) involves type 1 and type 2 inflammation. Biologics targeting specific inflammatory pathways, such as IL-5 and IL-4/IL-13, may benefit certain COPD endotypes.
Inhaled treprostinil in pulmonary hypertension associated with COPD: PERFECT study results - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38811045/
The risk-benefit observations associated with iTRE in patients with PH-COPD did not support continuation of the PERFECT study. The results of this study do not support iTRE as a viable...
The PERFECT study found that inhaled treprostinil (iTRE) in PH-COPD patients increased the risk of serious adverse events and mortality, with no improvement in exercise capacity, leading to early termination of the trial.