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Relationship between polymorphisms in the TGF-β receptor gene and susceptibility towards chronic obstructive pulmonary disease in Northern Indians - PubMed

Relationship between polymorphisms in the TGF-β receptor gene and susceptibility towards chronic obstructive pulmonary disease in Northern Indians - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/41207879/

This study is the first in a North Indian cohort to identify the protective role of rs6478974 in COPD, emphasising the significance of TGFBR1 polymorphisms in disease pathogenesis and risk...

A North Indian study identified TGFBR1 gene variants influencing COPD risk. The rs6478974 variant showed a protective effect, highlighting TGF-β signaling polymorphisms in COPD susceptibility and genetic risk prediction.

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Fun Facts! Refining existing delivery systems can be just as impactful as developing new drugs. Particle size reduction enables deeper lung deposition, while inspiration-synced nebulizers and flow-controlled nasal delivery systems enhance pulmonary drug absorption. Innovations in aerosol dynamics optimize efficiency in both spontaneous and ventilated breathing.

What innovations in device design are boosting drug delivery efficiency and lung deposition in respiratory care?

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What innovations in device design are boosting drug delivery efficiency and lung deposition in respiratory care?

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Diaphragmatic dysfunction can lead to severe respiratory issues. Accurate diagnosis involves imaging and function tests, with ultrasound offering high precision. Treatments vary by cause, with noninvasive ventilation and pacing improving outcomes.

Learn how to assess and manage effectively

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Clinical and pathological characteristics of CRS with nasal polyps in patients with asthma-COPD overlap - PubMed

Clinical and pathological characteristics of CRS with nasal polyps in patients with asthma-COPD overlap - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/41135212/

CRS-ACO patients were prone to recurrence of nasal polyps, and the pathology of nasal polyps in CRS-ACO patients were significantly infiltrated with neutrophilic inflammatory cells. CRS-ACO patients revealed inflammatory cell...

Patients with chronic rhinosinusitis and asthma-COPD overlap showed faster nasal polyp recurrence and greater neutrophilic infiltration, supporting the “one airway, one disease” concept linking upper and lower airway inflammation.

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