Bisoprolol in Patients With Chronic Obstructive Pulmonary Disease at High Risk of Exacerbation: The BICS Randomized Clinical Trial - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38762800/
isrctn.org Identifier: ISRCTN10497306.
The Bisoprolol in COPD Study (BICS) found that bisoprolol treatment did not reduce COPD exacerbations in high-risk patients, with no significant difference in exacerbation rates or serious adverse events compared to placebo.
Home Noninvasive Ventilation in COPD - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38301744/
Evidence is increasing that long-term noninvasive ventilation (LTNIV) can improve outcomes in individuals with severe, hypercapnic COPD. Although the evidence remains unclear in some aspects, LTNIV seems to be able...
Long-term noninvasive ventilation (LTNIV) improves outcomes in severe hypercapnic COPD by reducing dyspnea, Pco2, rehospitalizations, and mortality, requiring proper interfaces and ventilation settings for efficacy and adherence.
Castleman disease of plasma cell type accompanied with bronchiolitis obliterans: a case report and review of the literature - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38082371/
Castleman disease is a rare lymphoproliferative disorder with a variety of symptoms. At present, the treatment of Castleman disease accompanied with bronchiolitis obliterans is mostly based on experiences or previous...
This case presents a 69-year-old male with Castleman disease and bronchiolitis obliterans, diagnosed via imaging and pathology, treated with surgery and immunosuppressive therapy, and stable without recurrence after 11 months.
Contribution of cuproptosis and Cu metabolism-associated genes to chronic obstructive pulmonary disease - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37801050/
Airway epithelial cell injury plays a crucial role in the pathogenesis of chronic obstructive pulmonary disease (COPD). However, a novel form of Cu-induced programmed cell death known as cuproptosis has...
This study highlights the involvement of cuproptosis and copper metabolism-related genes in COPD pathogenesis, suggesting elevated copper levels and key regulators as potential therapeutic targets for COPD treatment.
Analyses of Factors Associated with Acute Exacerbations of Chronic Obstructive Pulmonary Disease: A Review - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/38034468/
Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) is the exacerbation of a range of respiratory symptoms during the stable phase of chronic obstructive pulmonary disease (COPD). AECOPD is thus...
Acute exacerbations of COPD (AECOPD) significantly impact patient quality of life and survival. Standardized management, AI, and preventive systems can improve prognosis and reduce exacerbation risk, enhancing overall outcomes.