Opioids in Treatment of Refractory Dyspnea in Chronic Obstructive Pulmonary Disease: Yes, No or Maybe
Source : https://pubmed.ncbi.nlm.nih.gov/38541060/
Chronic Obstructive Pulmonary Disease (COPD) is a complex condition with significant impact on prognosis, especially in advanced stages where symptom burden becomes critical. Breathlessness affects patients' quality of life, and...
This paper reviews recent evidence on opioid use for managing breathlessness in COPD, assessing clinical benefits, inconsistencies, and identifying patient subgroups that might benefit from opioid therapy.
Extrapulmonary Comorbidities Associated with Chronic Obstructive Pulmonary Disease: A Review
Source : https://pubmed.ncbi.nlm.nih.gov/38476124/
Most patients with chronic obstructive pulmonary disease (COPD) suffer from at least one additional, clinically relevant chronic disease. To a degree, the high global prevalence and mortality rate of COPD...
COPD patients often have comorbidities like cardiovascular disease, diabetes, and osteoporosis. These conditions interact, affecting prognosis and care. Improved management and individualized strategies are needed.
Cellular and Molecular Biology of Mitochondria in Chronic Obstructive Pulmonary Disease
Source : https://pubmed.ncbi.nlm.nih.gov/39063022/
Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder characterized by enduring airflow limitation and chronic inflammation. Growing evidence highlights mitochondrial dysfunction as a critical factor in COPD development...
Mitochondrial dysfunction plays a key role in COPD, affecting cellular function and disease progression. Targeted therapies and mitochondrial biomarkers offer promising avenues for improved management and patient outcomes.
Phenotype to Treatable Traits-Based Management in Chronic Obstructive Pulmonary Disease
Source : https://pubmed.ncbi.nlm.nih.gov/38882972/
Chronic obstructive pulmonary disease (COPD), a heterogeneous respiratory disease driven by various genetic and environmental factors, presents significant challenges in diagnosis and management. Traditional approaches focused on phenotypic classification, but...
Embracing treatable traits-based management in COPD offers personalized interventions, enhancing symptom control and clinical outcomes, and improving the quality of life for patients through tailored approaches.

