micro-community-banner
 
  • Saved

4mo
COPD care gaps: Cognitive impairment management insights from Saudi HCWs

Cognitive impairment (CI) is a critical yet often overlooked comorbidity in chronic obstructive pulmonary disease (COPD). A 2025 study by Siraj et al. examined healthcare workers’ (HCWs) perceptions and practices in Saudi Arabia, revealing that while most HCWs recognize CI’s detrimental effects on COPD management, few feel equipped to address it.

Highlights

  • 83% of HCWs believe CI contributes to underdiagnosis; 81% associate it with poor self-management and misdiagnosis
  • Only 3% felt fully confident managing CI-related behaviors or discussing a diagnosis
  • Fewer than 45% actively assess CI during patient visits
  • Common detection cues include psychiatric symptoms (84.5%), family history (76.4%), and memory loss (63.7%)
  • Top barriers include poor training (64%), limited knowledge (64%), lack of protocols (58%), and time constraints (53%)

What Sets This Study Apart

As one of the first regional analyses, this study identifies factors—such as male gender, therapist roles, and ≥10 years’ experience—linked to better CI recognition, offering targets for future training.

Limitations

Findings are self-reported and geographically limited, reducing external validity. Patient outcomes were not assessed.

Could targeted interdisciplinary training help close current care gaps for COPD patients with cognitive impairment?

  • Saved

4mo
Risk Factors and Outcomes in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease - PubMed

Risk Factors and Outcomes in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/41001282/

Introduction Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a common cause of hospitalization and is associated with significant morbidity, mortality, and healthcare burden. Objectives To determine the risk...

Retrospective study of 355 COPD patients hospitalized for acute exacerbations identified smoking, comorbidities, and advanced age as predictors of poor outcomes, underscoring the need for early risk assessment and targeted management.

  • Saved

4mo
TET1 Alleviates Cigarette Smoke Induced Bronchial Epithelial Cell Apoptosis Through Upregulating Nrf2 - PubMed

TET1 Alleviates Cigarette Smoke Induced Bronchial Epithelial Cell Apoptosis Through Upregulating Nrf2 - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/40970227/

Reduced Nrf2 expression in COPD may result from promoter hypermethylation. TET1 directly binds and demethylates the Nrf2 promoter, restoring its expression and attenuating CSE-induced HBE cells apoptosis. These findings identify...

This study shows that TET1 reduces cigarette smoke–induced apoptosis in bronchial epithelial cells by upregulating Nrf2, highlighting an epigenetic mechanism that may mitigate oxidative stress and airway damage in COPD.

  • Saved

4mo
Adherence to the Chronic Obstructive Pulmonary Disease Guidelines in Primary Care: The Greek COPD COCARE study - PubMed

Adherence to the Chronic Obstructive Pulmonary Disease Guidelines in Primary Care: The Greek COPD COCARE study - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/40945752/

Our results show that adherence to COPD guidelines among GPs is suboptimal and varies between rural and urban settings. Such information must be accounted for by health care professionals and...

The Greek COPD COCARE study found high adherence to smoking cessation, vaccination, and comorbidity recording guidelines but significant gaps in inhaled therapy prescriptions, pulmonary rehabilitation referrals, and monitoring practices, especially across rural-urban settings.

  • Saved

4mo
Disease burden and health-related outcomes of patients discharged from hospital following a COPD exacerbation in the United States - PubMed

Disease burden and health-related outcomes of patients discharged from hospital following a COPD exacerbation in the United States - PubMed

Source : https://pubmed.ncbi.nlm.nih.gov/40907834/

Treatment patterns post-hospitalization for a COPD exacerbation in the U.S. don't align with recognized standards (e.g. GOLD recommendations). Patients discharged from hospital post-COPD exacerbation have a high risk of severe...

This U.S. observational study highlights high post-discharge risks—cardiopulmonary events, readmissions, and mortality—among COPD patients, with suboptimal adherence to GOLD-aligned therapy, underscoring critical gaps in post-hospitalization management and timely treatment escalation.