Implementing Psychological Interventions Delivered by Respiratory Professionals for People With COPD: a Stakeholder Interview Study
Source : https://www.nature.com/articles/s41533-023-00353-8
Implementing psychological interventions in healthcare services requires an understanding of the organisational context. We conducted an interview study with UK National Health Service stakeholders to understand the barriers and facilitators...
People need support with physical and psychological symptoms inherent with COPD and healthcare should be provided holistically. Respiratory healthcare professionals are considered able to provide psychologically informed approaches, but resources must be available for training, staff supervision and service integration.
Role of Prostanoids, Nitric Oxide and Endothelin Pathways in Pulmonary Hypertension Due to COPD
Source : https://www.frontiersin.org/articles/10.3389/fmed.2023.1275684/full
Pulmonary hypertension (PH) due to chronic obstructive pulmonary disease (COPD) is classified as Group 3 PH, with no current proven targeted therapies. Studies suggest that cigarette smoke, the most risk...
This review aims to shed light on the role of impaired prostanoids, nitric oxide and endothelin pathways in cigarette smoke- and hypoxia-induced pulmonary vascular remodelling and also discusses the potential of using these pathways as therapeutic target for patients with PH secondary to COPD.
Endobronchial Valve Treatment in Chronic Obstructive Pulmonary Disease: a Qualitative Study of Patients' Expectations
Source : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10576923/
Endobronchial valve (EBV) treatment is a treatment option for selected patients with severe chronic obstructive pulmonary disease (COPD) to reduce dyspnea and improve quality of life.
Living a life of considerably reduced quality, patients might have an increased focus on potential positive effects of EBV treatment while filtering out information about potential side effects. This might bias their decision-making process.
How Inhaled Corticosteroids Target Inflammation in COPD
Source : https://err.ersjournals.com/content/32/170/230084.long
Inhaled corticosteroids (ICS) are the most commonly used anti-inflammatory drugs for the treatment of COPD. COPD has been previously described as a "corticosteroid-resistant" condition, but current clinical trial evidence shows...
This review describes the components of inflammation modulated by ICS in COPD and the reasons for the variation in response to ICS between individuals.
Association Between the Oxidative Stress Gene Polymorphism and Chronic Obstructive Pulmonary Disease Risk: a Meta-Analysis
Source : https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890-023-02625-y
The association between the oxidative stress gene polymorphism and chronic obstructive pulmonary disease (COPD) risk has been extensively studied but the results have been controversial. This study aimed to investigate...
Our results confirm that oxidative stress gene polymorphism was associated with COPD risk. These finding can improve human understanding of this disease gene molecular level and enable early intervention and prevention of COPD.