Changes in mortality among patients with chronic obstructive pulmonary disease from the 1990s to the 2000s: a pooled analysis of two prospective cohort studies
Source : https://bmjopen.bmj.com/content/13/3/e065896
Objectives This study aimed to identify and investigate changes in the mortality of patients with chronic obstructive pulmonary disease (COPD) at the same institute from the 1990s to the 2000s....
Conclusions: Trends indicating a better prognosis for patients with COPD in the 2000s were observed. This improvement may be associated with the usage of LABDs.
Altered long non-coding RNAs expression in normal and diseased primary human airway epithelial cells exposed to diesel exhaust particles - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36877189/
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Conclusions: Overall, our work highlights the potential importance of lncRNAs in regulating DEP-induced gene expression changes associated with carcinogenesis, and individuals suffering from COPD are likely to be more vulnerable to these environmental triggers.
Efficacy of once-daily, single-inhaler, fixed-dose combination of mometasone/indacaterol/glycopyrronium in patients with asthma with or without persistent airflow limitation: Post hoc analysis from the IRIDIUM study - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/36906187/
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Conclusions: Once-daily fixed-dose MF/IND/GLY was efficacious in asthma patients with and without persistent airflow limitation.
Factors Affecting Patient Adherence to Inhalation Therapy: An Application of SEIPS Model 2.0
Chronic respiratory diseases such as asthma and Chronic Obstructive Pulmonary Disease (COPD) are perceived as serious public health problems in the overall population. Inhalation therapy is the foundation stone for...
Conclusion: The findings of the study identified 10 influential factors that impact on patient adherence to inhalation therapy. A SEIPS-based conceptual model was constructed based on the responses of patients and HCPs to explore the experiences of patients engaging in inhalation therapy and interacting with inhalation devices. In particular,...
“This is What Lies Ahead”. Perspectives of Oxygen-Naïve COPD Patients on Long-Term Oxygen Use. A Qualitative Study
Chronic obstructive pulmonary disease (COPD) is a highly prevalent, life-threatening lung disease. Due to its chronic course and its huge impact on quality of life, COPD is a major cause...
Conclusion: The message that home oxygen should be started, was regarded as bad news by most participants. The rationale behind the therapy and the way it is delivered were unknown to most participants. Some participants anticipated smoking-related stigma and social isolation. Misconceptions such as tank explosions, becoming housebound, full...