Association Between Chronic Obstructive Pulmonary Disease and All-Cause Mortality After Aortic Valve Replacement for Aortic Stenosis
Source : https://www.ajconline.org/article/S0002-9149(22)01189-4/fulltext
Chronic obstructive pulmonary disease (COPD) and aortic stenosis (AS) are the most common diseases in which age plays a major role in the increase of their prevalence and when they...
Conclusions: In this study, 1/3 of patients with severe AS undergoing AVR had COPD. COPD was independently associated with all-cause mortality after AVR.
Relationship between COPD and GERD: a bibliometrics analysis | COPD
Chronic obstructive pulmonary disease (COPD) is a chronic and progressive condition in which the airways are inflamed, and airflow is limited in a nonreversible manner. There is a high likelihood...
Conclusion: Research on COPD and GERD has flourished, and its content topics have become more in-depth over time. In the future, this hot topic deserves more attention.
![Discovery of the novel Benzo[b]thiophene 1,1-dioxide derivatives as a potent STAT3 inhibitor against idiopathic pulmonary fibrosis](https://static-content-prd.skipta.com/public/skipta/skipta-post/2023-02/1-s2.0-S0223523422008558-ga1.jpg "Discovery of the novel Benzo[b]thiophene 1,1-dioxide derivatives as a potent STAT3 inhibitor against idiopathic pulmonary fibrosis")
Discovery of the novel Benzo[b]thiophene 1,1-dioxide derivatives as a potent STAT3 inhibitor against idiopathic pulmonary fibrosis
Source : https://www.sciencedirect.com/science/article/abs/pii/S0223523422008558?via=ihub
Through molecular docking, Based on Stattic a series of new STAT3 inhibitor with BTP core were synthesized. * Structure-activity relationship studies finally yielded a more potent compound 10K, with potency...
Conclusion: Taken together, these results suggest that 10K could be a potential STAT3 inhibitor for the treatment of IPF.
Discriminant Validity of a Single Clinical Question for the Screening of Inactivity in Individuals Living with COPD
Chronic and progressive dyspnoea is the most characteristic symptom of chronic obstructive pulmonary disease (COPD), which, in turns, reduces patient's physical activity. Additionally, the reduction in physical activity leads to...
Conclusion: The present results indicate that self-reported brisk walk time lower than 30 min/day may be a valid tool for the screening of inactivity in individuals living with COPD in routine care, if more detailed physical activity measures are not feasible.
Inhalation therapies in COPD - adverse drug reactions impact on emergency department presentations - European Journal of Clinical Pharmacology
Source : https://link.springer.com/article/10.1007/s00228-022-03433-9
Purpose Inhaled drugs have been cornerstones in the treatment of chronic obstructive pulmonary disease (COPD) for decades and show a high prescription volume. Due to the local application, drug safety...
Conclusion: Overdosed inhaled therapies in patients with COPD lead to relevant ADRs and impact on emergency room presentations. These are rarely associated to inhaled therapy by healthcare professionals or patients. Due to the high volume of inhaled drug prescriptions, pharmacovigilance and patient education should be more focused in patients...