Inhaler Triple Therapy for COPD | COPD
Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disease, characterized by persistent airflow limitation and increased breathlessness. COPD is a leading cause of morbidity and mortality, and is the...
Conclusion: First-time triple therapy was frequently initiated in patients with COPD inadequately controlled on maintenance therapy. General practitioners in England generally identify appropriate patients who require initiation of triple therapy.
Chronic Obstructive Pulmonary Disease and Lung Cancer: A Review for Clinicians - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35790131/
Chronic obstructive pulmonary disease (COPD) and lung cancer (LC) are common global causes of morbidity and mortality. Because both diseases share several predisposing risks, the two diseases may occur concurrently...
Conclusion/Relevance: In this monograph, we review the mechanistic linkage between LC and COPD, the impact of LC screening in patients at risk, and the implications of the presence of COPD on the approach to the diagnosis and treatment of LC. This manuscript succinctly reviews the epidemiology and common pathogenetic factors for the concurrence...
Effectiveness of Treatment With Dual Bronchodilation (LABA/LAMA) Compared With Combination Therapy (LABA/ICS) for Patients With COPD: A Population-Based Study
Source : https://www.sciencedirect.com/science/article/pii/S0300289622003374?via=ihub
Available online 13 May 2022 Initiation of treatment of COPD with a combination of a long-acting beta-agonist (LABA) and an inhaled corticosteroid (ICS) is frequent irrespective of the risk of...
Conclusion: Initiation of treatment with LABA/LAMA was associated with a lower risk of exacerbation and escalation to triple therapy compared to LABA/ICS in the majority of patients with COPD in primary care.
Inhaled Beta2-Agonists Initiation and Risk of Major Adverse | COPD
Asthma and chronic obstructive pulmonary diseases (COPD) are the two principal diagnoses of Obstructive Airways Diseases (OADs). Beta (β) 2-adrenergic agonists are the frontline treatment for these diseases. They exert...
Conclusion: Patients initiating treatment with LAMA LABA had more severe COPD than patients prescribed LAMA. The proportion of patients experiencing clinical worsening was similarly high in both cohorts, suggesting that early identification and treatment optimization are necessary.
Prescribing patterns of long-acting bronchodilators for COPD | COPD
Why was the study done? Guidelines for the treatment of patients with chronic obstructive pulmonary disease (COPD) are largely based on the results of clinical trials. However, clinical practice can...
Conclusion: Patients initiating treatment with LAMA LABA had more severe COPD than patients prescribed LAMA. The proportion of patients experiencing clinical worsening was similarly high in both cohorts, suggesting that early identification and treatment optimization are necessary.