Occupational exposure to fine particulate matter in the reinforced concrete production and its association with respiratory symptoms and lung function - BMC Public Health
Source : https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-023-16753-x
Background Reinforced concrete production is widespread, but little is known about the occupational exposure to fine particulate matter (PM) in such workplaces, including from metalworking and concrete processing. Therefore, the...
Mixing concrete and metalworks pose the greatest risk for worker’s health in the reinforced concrete production from the inhalational exposure to aerosol, adversely affecting respiratory health.
Lung volumes differentiate the predominance of emphysema versus airway disease phenotype in early COPD: an observational study of the COPDGene cohort
Source : https://openres.ersjournals.com/content/9/5/00289-2023
Rationale Lung volumes identify the "susceptible smokers" who progress to develop spirometric COPD. However, among susceptible smokers, development of spirometric COPD seems to be heterogeneous, suggesting the presence of different...
Lung volumes identify distinct physiological and radiographic phenotypes in early disease among susceptible smokers and predict the rate of spirometric disease progression and the severity of symptoms in early COPD.
The Abnormal Alternations of Brain Imaging in Patients with Chronic Obstructive Pulmonary Disease: A Systematic Review
Source : https://content.iospress.com/articles/journal-of-alzheimers-disease-reports/adr220083
Background: Cognitive impairment (CI) is an important extrapulmonary complication in patients with chronic obstructive pulmonary disease (COPD). Multimodal Neuroimaging Examination can display changes in brain structure and functions in patients...
Conclusion: CI in patients with COPD may present as a type of dementia different from Alzheimer's disease, which tends to manifest as frontal cognitive decline early in the disease.
Inhaled therapies targeting prostacyclin pathway in pulmonary hypertension due to COPD: systematic review
Source : https://www.frontiersin.org/articles/10.3389/fmed.2023.1217156/full
BackgroundPulmonary hypertension due to chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD) is classified as group 3 pulmonary hypertension. Inhaled treprostinil, a prostaglandin I2 analogue also known as...
Conclusion: This systematic review demonstrated that although inhaled prostacyclin does not seem to improve COPD-related outcomes (e.g., lung function and exercise capacity), short-term use of inhaled prostacyclin has the potential to reduce mean pulmonary artery pressure and pulmonary vascular resistance without impairing...
Home noninvasive ventilation use in patients hospitalized with COPD - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/37525442/
Approximately half of individuals with at least one COPD-related hospitalization have CompHRF, but only 8.2% of those use home NIV. Future studies should estimate CHRF rates and the degree of...
Conclusion: Approximately half of individuals with at least one COPD-related hospitalization have CompHRF, but only 8.2% of those use home NIV. Future studies should estimate CHRF rates and the degree of underutilization of home NIV in larger multicenter samples.