Development and Clinical Applications of a Virtual Imaging Framework for Optimizing Photon-counting CT - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35611365/
The purpose of this study was to develop a virtual imaging framework that simulates a new photon-counting CT (PCCT) system (NAEOTOM Alpha, Siemens). The PCCT simulator was built upon the...
Conclusions/Relevance: Our developed virtual imaging platform enables systematic comparison of new PCCT technologies as well as optimization of the imaging parameters for specific clinical tasks.
The new era of add-on asthma treatments: where do we stand? - Allergy, Asthma & Clinical Immunology
Source : https://aacijournal.biomedcentral.com/articles/10.1186/s13223-022-00676-0
Globally, a small proportion (5-12%) of asthma patients are estimated to have severe disease. However, severe asthma accounts for disproportionately high healthcare resource utilization. The Global Initiative for Asthma (GINA)...
Conclusion/Relevance: In the future, both biologics and small molecules will continue to play key roles in the individualized treatment of severe asthma. However, as targeted therapies, their application will continue to be focused on patients with certain phenotypes who meet the specific criteria for use as identified in pivotal clinical trials.
Prevalence, incidence, morbidity and mortality rates of COPD in Saudi Arabia: Trends in burden of COPD from 1990 to 2019
Source : https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0268772
Background The available data to determine the chronic obstructive pulmonary disease (COPD) burden in Saudi Arabia are scarce. Therefore, this study closely examines and tracks the trends of the COPD...
Conclusion: Over the period 1990–2019, the prevalence and incidence of COPD in Saudi Arabia have been steadily rising. Even though COPD morbidity and death rates have been decreasing, they remain higher in men and older age. The holistic assessment and interventions with careful attention to optimising the community-based primary care...
Factorial analysis of N-acetylcysteine and propolis treatment effects on symptoms, life quality and exacerbations in patients with Chronic Obstructive Pulmonary Disease (COPD): a randomized, double-blind, placebo-controlled trial - PubMed
Source : https://pubmed.ncbi.nlm.nih.gov/35587070/
Objective: Standard treatment for chronic obstructive pulmonary disease (COPD) includes inhalation therapy along with mucoactive drugs. The aim of this study was to assess the efficacy and safety of orally...
Conclusions: Treatment with high NACp for 6 months is safe and beneficial for cough and expectoration symptoms and improves the life quality. NACp significantly reduces acute exacerbation frequency in COPD patients by controlling COPD related symptoms.
Physiological effects of high-intensity versus low-intensity noninvasive positive pressure ventilation in patients with acute exacerbation of chronic obstructive pulmonary disease: a randomised controlled trial - Annals of Intensive Care
Source : https://annalsofintensivecare.springeropen.com/articles/10.1186/s13613-022-01018-4
Background High-intensity noninvasive positive pressure ventilation (NPPV) is a novel ventilatory approach to maximally decreasing elevated arterial carbon dioxide tension (PaCO2) toward normocapnia with stepwise up-titration of pressure support. We...
Conclusions: High-intensity NPPV is more effective than low-intensity NPPV at decreasing elevated PaCO2, reducing inspiratory effort, and alleviating dyspnoea in AECOPD patients.